该团队在《International Immunopharmacology》期刊上发表了题为“LPS-induced vein endothelial cell injury and acute lung injury have Btk and Orai 1 to regulate SOC-mediated calcium influx”的论文。实验通过RNA体内转染试剂(EntransterTM-in vivo, Engreen)获得Orai 1与Btk的基因敲除小鼠模型,证实了这两个基因调控钙超载与急性肺损伤的作用,揭开肺病研究的新机制。